David Brooks et. al.
I have watched with interest the problems related to getting screens and printer profiles to work properly.
I have an iMac 24 and an Epson R1800. I calibrate using the Spyder3elite system. I am not endorsing any of these but am finding you really can match the screen and your prints.
David has been right about the back lighting being much too bright. However by playing with my room light I was able to get my calibration within Spyder's acceptable parameters. That is important.
I next got in contact with a senior software developer at Datacolor. Was I ever in for some corrective education. Clicking on all the correct selections in order to print target patches that can be read properly is really, really important.
I finally arrived at an acceptable printer profile. Now I am playing with some of their presets and tweaking the sliders to make skin tones look good and on and on.
I am finally having fun in this printing business although I better order some more paper.
I will be doing customers proofs in house again and saving real time.
Color calibration is complicated but one really can work through it and be successful.